The DeSci Guide: Is Decentralized Science the New Web 3.0 Trend?by@strateh76
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The DeSci Guide: Is Decentralized Science the New Web 3.0 Trend?

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With the advent and development of blockchain, the world began to strive for openness, transparency, and decentralization in many industries. DeSci is betting on DAOs - stand-alone, autonomous organizations that will solve individual research challenges. Scientists will be able to find solutions to fundamental problems faster, publish results, protect authors' reputation and protect their work. DeFi will provide opportunities for scientists worldwide to join teams like NFTs and cloud labs. This borderless knowledge of borderless progress will drive progressless progress.

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With the advent and development of blockchain, the world began to strive for openness, transparency, and decentralization in many industries. In just a few years, blockchain from Bitcoin and payment systems began to open up more and more facets of its usefulness to humanity, making finance decentralized and the world of art and creativity more open to talented people. In less than 10 years, concepts of NFT, DeFi, metauniverses, and web 3.0 have become widespread. So it is unsurprising that the subsequent discovery was DeSci - decentralized science.

Recent years have seen breakthroughs in many areas of science - such as the discovery of RNA vaccines, genetic engineering advances, and successful fusion experiments.

But I will examine whether science is evolving as a fundamental field or its long-established system is slowing the emergence of necessary new research in this article.

What are the problems in science and basic research?

Science is very centralized and often controlled by state institutions. Scientists' hands are essentially tied because they depend on funding and approval from certain regulators who decide what to study and what not to study. States often have favorite industries, such as medicine and IT, and there are rogue fields, such as climate change research. The community of scientists pushing the new concept of DeSci talk about several global problems with modern science.

One of the biggest challenges is funding basic research. Getting funds hinders science development and remains one of the most significant concerns for scientific researchers. Scientists spend a lot of time filling out grant applications. But they may never see money for their ideas because their field touches someone else's business interests, their ranking is not high enough in the global community, or the field of research does not care about government institutions.

The use of blockchain technology, advances in DeFi, NFT, and the organization of specialized DAO blockchain projects can help create sustainable channels for the flow of funds. Similarly, the problem of funding scientific research can be solved by selling commercial research or receiving royalties through blockchain for the use of scientists' research data.

Another problem is access to information about the research. This is another global problem that DeSci can solve. Many scientific studies are private. Making them accessible is one of the main objectives of the DeSci with the help of DAO decisions. This could also include using smart contracts to move away from intermediaries who profit from information exchange and peer review of computer science research. At the same time, it is expensive to publish in the most influential scientific journals, so not all talented people can afford to tell the world about their discoveries. For example, an article in the prestigious medical journal The Lancet costs $6500, and an article in Nature costs $11000. In addition, these journals are sometimes criticized for their dependence on national health institutions or other funding sources.

A third problem is a political interference in science and a lack of transparency. Fighting political pressure and censorship with blockchain data is possible. Thanks to blockchain data, scientists and researchers can anonymously and securely store, share and access their scientific challenge data from anywhere in the world. At the same time, the research approach is often subjective. This also applies to the conditional lists of approved scientists and areas of science that high-ranking officials in ministries want to develop and various conspiracy theories about the influence of big pharma on lobbying their interests in the study of finding cures for chronic diseases.

The DAO network in DeSci can help solve the problems of centralized science

DeSci is betting on DAOs - stand-alone, autonomous organizations that will solve individual research challenges. And the variety of tools that blockchain provides will help make science more independent. For example, blockchain in science can:

  • Use DeFi tools to address research funding challenges. Already existing science DAOs provide several funding options, from crowdfunding and research token staking to the sale of utility NFTs. For example, under the terms of smart contracts, part of the earnings from commercially successful scientific discoveries will be able to go back to the DAO. Another example is fundraising for scientific projects - in theory, anyone with a rare disease would be able to participate in funding research to find a cure more quickly.
  • Eliminate the middleman between researchers and reviewers. Currently, scientists review their colleagues' work for free, and the profits are captured by an intermediary - some scientific community or journal. Blockchain with smart contracts would be able to eliminate the expensive middleman and connect scientists with reviewers around the world. It would make science faster.
  • Validate a scientist's reputation in an unbiased manner. Right now, scientists' reputations depend on the h-index, which considers the number of publications and significant awards. This method is not wrong in and of itself, but it has drawbacks. For example, some scientists have to increase the number of publications without paying much attention to the quality of research just to get access to funding. Publishing for the sake of ranking is an empty job that hinders science. DeSci activists propose replacing the h-index with the NFT, which would consider not only an author's publications but also other important work, such as expertise, teaching successes, mentoring, and participation in research by other scientists.
  • Make science truly open to the world. DeSci can encourage scientists worldwide to join teams of like-minded scientists, regardless of their background or the political climate in their countries. It is possible, for example, in the form of online co-laboratories and cloud labs. This borderless sharing of knowledge will drive progress. Scientists will be able to find solutions to fundamental problems faster, publish collaborative results, and protect authorship through the opportunities that NFTs provide.

These are 4 benefits of DeSci that make this new area prospective. DeSci has been experimenting with blockchain data technology to improve the scientific environment and science in general. With the new methods, DeSci expects to empower scientists from different industries and achieve new scientific results to accelerate progress.

What scientific challenges are already being addressed by DeSci?

Decentralized science is just beginning to develop, but organizations are already emerging that bring together scientists around the world. The DeSci ecosystem consists of several foundations, research centers, and platforms for publishing scientific data.

Some DAOs aim to solve specific difficulties related to the science system. For example, to solve the funding problem, to provide a platform for the publication of scientific research, to gather an independent board of experts, etc. Other DAOs focus on specific areas of science, such as climate problems, breakthrough medicine, or longevity research. Here are a few examples of organizations.

The Molecule Project is a fundraising platform for biotechnology research. Currently, about 40 scientists on the website are looking for funds for their projects. Anyone can donate and support important future discoveries. For example, the studies include the search for antibodies to the still incurable Alzheimer's disease, effective treatment for autoimmune diseases, and psoriasis therapy. Several projects have already raised the necessary funds for the first phase of trials.

VitaDAO is exploring life extension. Longevity is one of the popular topics for DeSci, and is quickly raising the necessary funds. 5,000 scientists have gathered under the society's wing, 200+ projects have been published, and over $2.5 million has been raised in a short time.

Antidote DAO is looking for effective cures for cancer. The founders of this organization have nothing to do with science, but they understand blockchain technology. With the help of the crypto community, they raise funding for the most audacious research to find new cures for a disease that is killing millions of people worldwide.

Dynamiculture stimulates research in the field of environmental protection. This field includes air and water pollution, biodiversity reduction, the food crisis, and other vital eco-problems of recent decades. The community has issued tokens that scientists worldwide can earn for helping the DAO fight climate change.


The products of decentralization are used by many people in different fields of business, art, and science. Just as cryptocurrencies and DeFi are changing modern finance, NFT the art market, DAO the business environment, the DeSci phenomenon emerged at the intersection of science, art, and entrepreneurship to change approaches to health science development and research.

This movement emerged in response to the excessive concentration of funding in the dominant centers of science and information needed to advance scientific challenges primarily because they can limit access to funding for their purposes.

These days, access to funding, data, and cutting-edge tools can be limited for various reasons, as recent practice has shown, including political ones. Simply put, DeSci is a decentralized environment that allows the creation of an automated system for addressing the scientific challenge and fair distribution of funds for scientific research. To this, we can add the possibility to freely expand the cooperation of scientists in these fields without any borders and intermediaries.

So far, scientists have only just begun to come together in decentralized communities. DeSci activists are assembling panel discussions at significant blockchain conferences to gather talented researchers quickly and, most importantly, investors who will believe in their ideas. The work has just begun, so none of the organizations can yet boast prominent scientific accomplishments, but the scientists have started to find funding, which means results will emerge. Soon, the term “DeSci” will be as popular as “ICO” in 2018.

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