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In chemistry, the universal measurement of a quantity is the mole. The mole is a very big unit of quantity, as the atoms and molecules are extremely small units to count. We quantify elements and compounds in a bigger measurement, the moles instead. A mole of a substance contains Avogadro's number of molecules in it which equals 6.022 x 1023. In a chemical equation that is needed to be balanced, the number 1 mole corresponds to the molecule's molecular weight in grams.