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Missouri located in the heart of the united states has a rich history of entrepreneurship dating back to the 1800s the states central location and diverse population have made it a hub for innovation and business growth the area is home to several universities including the university of missouri and washington university in st louis which have produced many successful entrepreneurs in recent years missouri has seen a surge in technological innovation with companies like square and lockerdome being founded in the area additionally several major companies including anheuserbusch and express scripts are headquartered in missouri the state has a relatively low cost of living with a living wage of 1030 per hour however the unemployment rate is slightly higher than the national average at 42 the city level gdp is 300 billion with a rate of new companies starting and ending being relatively stable despite some challenges missouris startup scene is thriving due to its central location diverse population and supportive business environment the state government has implemented several initiatives to support entrepreneurship including tax incentives and funding programs with a growing number of successful startups and a supportive ecosystem missouri is poised to continue its growth as a hub for innovation and business