Authors: (1) Shih-Tang Su, University of Michigan, Ann Arbor (shihtang@umich.edu); (2) Vijay G. Subramanian, University of Michigan, Ann Arbor and (vgsubram@umich.edu); (3) Grant Schoenebeck, University of Michigan, Ann Arbor (schoeneb@umich.edu). Table of Links Abstract and 1. Introduction 2. Problem Formulation 2.1 Model of Binary-Outcome Experiments in Two-Phase Trials 3 Binary-outcome Experiments in Two-phase Trials and 3.1 Experiments with screenings 3.2 Assumptions and induced strategies 3.3 Constraints given by phase-II experiments 3.4 Persuasion ratio and the optimal signaling structure 3.5 Comparison with classical Bayesian persuasion strategies 4 Binary-outcome Experiments in Multi-phase trials and 4.1 Model of binary-outcome experiments in multi-phase trials 4.2 Determined versus sender-designed experiments 4.3 Multi-phase model and classical Bayesian persuasion and References 2.1 Model of Binary-Outcome Experiments in Two-Phase Trials We end this section by emphasizing that this model is the only non-trivial two-phase trial configuration when determined and designed experiments coexist. In other configurations such that some of the phase-II experiments can be designed by sender, the model can be reduced to a corresponding single-phase trial in the sense that the single-phase trial will yield the same payoffs for both sender and receiver when they play optimally. (Note that the reduced model may have a different prior if the experiment in phase-I is determined). This paper is available on arxiv under CC 4.0 license. Authors: (1) Shih-Tang Su, University of Michigan, Ann Arbor (shihtang@umich.edu); (2) Vijay G. Subramanian, University of Michigan, Ann Arbor and (vgsubram@umich.edu); (3) Grant Schoenebeck, University of Michigan, Ann Arbor (schoeneb@umich.edu). Authors: Authors: (1) Shih-Tang Su, University of Michigan, Ann Arbor (shihtang@umich.edu); (2) Vijay G. Subramanian, University of Michigan, Ann Arbor and (vgsubram@umich.edu); (3) Grant Schoenebeck, University of Michigan, Ann Arbor (schoeneb@umich.edu). Table of Links Abstract and 1. Introduction Abstract and 1. Introduction 2. Problem Formulation 2. Problem Formulation 2.1 Model of Binary-Outcome Experiments in Two-Phase Trials 2.1 Model of Binary-Outcome Experiments in Two-Phase Trials 3 Binary-outcome Experiments in Two-phase Trials and 3.1 Experiments with screenings 3 Binary-outcome Experiments in Two-phase Trials and 3.1 Experiments with screenings 3.2 Assumptions and induced strategies 3.2 Assumptions and induced strategies 3.3 Constraints given by phase-II experiments 3.3 Constraints given by phase-II experiments 3.4 Persuasion ratio and the optimal signaling structure 3.4 Persuasion ratio and the optimal signaling structure 3.5 Comparison with classical Bayesian persuasion strategies 3.5 Comparison with classical Bayesian persuasion strategies 4 Binary-outcome Experiments in Multi-phase trials and 4.1 Model of binary-outcome experiments in multi-phase trials 4 Binary-outcome Experiments in Multi-phase trials and 4.1 Model of binary-outcome experiments in multi-phase trials 4.2 Determined versus sender-designed experiments 4.2 Determined versus sender-designed experiments 4.3 Multi-phase model and classical Bayesian persuasion and References 4.3 Multi-phase model and classical Bayesian persuasion and References 2.1 Model of Binary-Outcome Experiments in Two-Phase Trials We end this section by emphasizing that this model is the only non-trivial two-phase trial configuration when determined and designed experiments coexist. In other configurations such that some of the phase-II experiments can be designed by sender, the model can be reduced to a corresponding single-phase trial in the sense that the single-phase trial will yield the same payoffs for both sender and receiver when they play optimally. (Note that the reduced model may have a different prior if the experiment in phase-I is determined). This paper is available on arxiv under CC 4.0 license. This paper is available on arxiv under CC 4.0 license. available on arxiv